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 | Medical News Releases >
Medical News Releases
May 2008
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Suspected cause of type 1 diabetes caught "red-handed" for the first time
May 8,
2008 -- Scientists at the School of Medicine working with diabetic mice have examined in unprecedented detail the immune cells long thought to be responsible for type 1 diabetes. Researchers were able to examine the immune cells from isolated insulin-making structures in the pancreas known as the islets of Langerhans.
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Platypus genome explains animal's peculiar features; holds clues to evolution of mammals
May 7,
2008 --
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| Nicole Duplaix/Getty Images |
| The platypus genome explains the creature's fascinating features, from mammals, reptiles and birds. |
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The duck-billed platypus: part bird, part reptile, part mammal — and the genome to prove it. An international consortium of scientists, led by the School of Medicine, has decoded the genome of the platypus, showing that the animal's peculiar mix of features is reflected in its DNA. An analysis of the genome, published today in the journal Nature, can help scientists piece together a more complete picture of the evolution of all mammals, including humans.
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Researchers find way to make tumor cells easier to destroy
May 6,
2008 -- Tumors have a unique vulnerability that can be exploited to make them more sensitive to heat and radiation, researchers at the School of Medicine report. The University radiation oncology researchers found that tumors have a built-in mechanism that protects them from heat (hyperthermia) damage and most likely decreases the benefit of hyperthermia and radiation as a combined therapy.
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April 2008
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Experts discuss aging's impact on ability to drive, find other transportation
April 28,
2008 -- Ensuring that the elderly have access to transportation while preventing age-related driving impairments will be the focus of the eighth annual Friedman Conference on Aging, "Are We Licensed for Life? Transportation and Driving Issues in an Aging Society."
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Environment influences when drinking begins; genes' role increases in transition to alcohol dependence
April 22,
2008 -- The influence of genetics increases as young women transition from their first drink to alcohol dependence. A team of researchers at the School of Medicine found that although environment is most influential in determining when drinking begins, genes play a larger role in advancing to problem drinking and alcohol dependence.
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Many African-Americans have a gene that prolongs life after heart failure
April 20,
2008 -- About 40 percent of African-Americans have a genetic variant that can protect them after heart failure and prolong their lives, according to research conducted at the School of Medicine and collaborating institutions. The genetic variant has an effect that resembles that of beta blockers, drugs widely prescribed for heart failure. The new study offers a reason why beta blockers don't appear to benefit some African-Americans.
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Readily available treatment could help prevent heart disease in kidney patients
April 17,
2008 -- The estimated 19 million Americans living with chronic kidney disease (CKD) face a high risk of death from cardiovascular disease, usually related to high levels of blood phosphate. Now researchers at the School of Medicine have demonstrated that high blood phosphate directly stimulates calcification of blood vessels and that phosphate-binding drugs can decrease vascular calcification.
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Washington University in St. Louis and AstraZeneca announce Alzheimer's research collaboration
April 17,
2008 -- The School of Medicine and the pharmaceutical company AstraZeneca (NYSE:AZN) have announced a research collaboration that aims to develop new and improved ways to diagnose and treat Alzheimer's disease. The major focus of the alliance will be biomarkers, characteristic changes in the brain and spinal fluid that physicians can use to diagnose Alzheimer's disease and track its response to treatment.
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Researchers close in on origins of main ingredient of Alzheimer's plaques
April 9,
2008 -- The ability of brain cells to take in substances from their surface is essential to the production of a key ingredient in Alzheimer's brain plaques, neuroscientists at the School of Medicine have learned. The researchers used a drug to shut down the intake process, known as endocytosis, in a mouse model of Alzheimer's disease. The change led to a 70 percent drop in levels of amyloid beta, the protein fragment that clumps together to form Alzheimer's plaques.
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Barch named new director of Conte Center
April 8,
2008 --
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| Barch |
The Silvio Conte Center for Neuroscience Research at Washington University has a new director. Deanna Barch, associate professor of psychology in Arts & Sciences, of psychiatry and of radiology, takes over leadership of the center from John Csernansky, the former Gregory B. Couch Professor of Psychiatry, who has become the chairman of psychiatry at Northwestern University.
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Surgeons announce advance in atrial fibrillation surgery
April 7,
2008 -- Heart surgeons at the School of Medicine report that by adding a simple 10-20 second step to an operative procedure they achieved a significant improvement in the outcome for the surgical treatment of atrial fibrillation (AF). The surgeons redirected wayward electrical impulses that cause AF by creating precisely placed scars, or ablations, in the heart muscle.
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