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(Excerpted from United Press International, Thursday,
March 15,
2007)

Anti-epileptic drugs may help hearing loss

NewsTrack - Science

U.S. medical scientists have discovered some anti-epileptic drugs might help prevent or treat noise-induced hearing loss.
On a battlefield, a soldier's hearing can be permanently damaged in an instant by the boom of an explosion and thousands of soldiers returning from Iraq have some permanent hearing loss. But now Washington University School of Medicine researchers in St. Louis have discovered a medicinal form of hearing protection might someday become a reality.
Associate Professor of otolaryngology Jianxin Bao has found two anti-epileptic drugs can prevent permanent hearing loss to a significant degree in mice exposed to loud noises.
Bao and colleagues discovered if they exposed mice to loud sounds and then gave them trimethadione (Tridione) or ethosuximide (Zarontin) -- both anticonvulsive medications used to treat epilepsy -- they could prevent a significant amount of permanent hearing loss. ...

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