The roots of alcoholism . . . in the genes?

Young people often begin drinking alcohol because of environmental factors, such as peer pressure. But genes appear to be a significant factor in determining whether drinking progresses to problem drinking and alcoholism, according to a new study by researchers at Washington University School of Medicine in St. Louis.

The study of 3,546 female twins, ages 18 to 29, examined how genes and environment influence drinking at different stages of life. The researchers found that genes accounted for about 30% of the timing of the first drink and for about 47% of the speed at which women progressed to alcohol dependence. But environmental factors, overall, seemed more influential, particularly earlier in life.

"That's good news in terms of modifying these behaviors and reducing the risk of developing alcohol dependence," says the study's lead author, Carolyn E. Sartor. "Genetics are not destiny, and our findings suggest that there are opportunities to intervene at all stages of alcohol use."

Most of the young women in the study curtailed their drinking before it advanced to problem drinking, maturing out of the behavior as they encountered lifestyle changes such as career moves, relationship commitments or starting a family. Those who don't may have genes that predispose them to alcoholism. Heavy partying into the late 20s may be a clue that a problem is developing, Sartor says. ...

•	The roots of alcoholism . . . in the genes? Health Los Angeles Times, Tuesday, April 29, 2008 Byline: Shari Roan