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WUSTL in the News Spotlight


(Excerpted from Innovations-Report (Germany), Saturday,
Jan. 24,
2004)

Two proteins may help prevent Alzheimer?s brain plaques

A study led by researchers at Washington University School of Medicine in St. Louis suggests two proteins work together in mice to prevent formation of brain plaques characteristic of Alzheimer's disease. "This is one of the first demonstrations in living animals that these proteins affect amyloid clearance," says David H. Holtzman, M.D., the Andrew B. and Gretchen P. Jones Professor and head of the Department of Neurology. "Our findings suggest it is worthwhile to explore the use of drugs or therapies to alter or perhaps increase the expression of these proteins as a potential treatment for Alzheimer's disease."

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