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DNA cornucopia
Amaizeing: Corn genome decoded
Nov. 19,
2009 --
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| Iowa State |
In recent years, scientists have decoded the DNA of humans and a menagerie of creatures but none with genes as complex as a stalk of corn, the latest genome to be unraveled. A team of scientists led by The Genome Center at the School of Medicine published the completed corn genome in the Nov. 20 journal Science, an accomplishment that will speed efforts to develop better crop varieties to meet the world's growing demands for food, livestock feed and fuel.
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A shared link
Decoding leukemia patient genome leads scientists to mutations in other patients
Aug. 5,
2009 -- Decoding the complete DNA of cancer patients is giving scientists at the School of Medicine a clearer picture of the complexity of the disease and allowing them to see intriguing and unexpected genetic relationships among patients.
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Human Microbiome Project
$19 million to WU scientists to decode microbe DNA and explore links to disease
June 23,
2009 --
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| Image courtesy of United States Department of Agriculture |
| Human gut bacterium Enterococcus faecalis |
The National Institutes of Health (NIH) has awarded scientists at Washington University School of Medicine in St. Louis four grants totaling $19 million to explore the trillions of microbes that inhabit the human body and determine how they contribute to good health and disease. The grants are part of the Human Microbiome Project, an ongoing, ambitious effort to catalog the bacteria, viruses, fungi and other microorganisms that naturally coexist in or on the body.
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What separates men from mice?
Of Mice and Men: Scientists unveil complete genome sequence of the mouse
May 29,
2009 -- Genetically speaking, what distinguishes a man from a mouse? U.S. and European scientists provide the answer in this week's PLoS Biology. They have described the finished genome sequence of the mouse, which, after the human, is only the second mammal to have its complete genome decoded.
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Pioneers, leaders in their respective fields
Washington University to award four honorary degrees at 148th Commencement
April 23,
2009 -- Washington University in St. Louis will bestow honorary degrees on four pioneers and leaders in their respective fields during its 148th Commencement May 15. During the ceremony, which will begin at 8:30 a.m. in Brookings Quadrangle, the university also will bestow more than 2,700 academic degrees on more than 2,600 students. Wendy Kopp, chief executive officer and founder of Teach For America, will deliver the Commencement address and receive an honorary doctor of humanities degree.
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What makes us human
Symposium draws top geneticists to discuss unique aspects of human DNA
March 19,
2009 -- A March 30th symposium will commemorate the 200th anniversary of Charles Darwin's birth by bringing together four leading geneticists whose research focuses on defining the DNA changes that distinguish humans from our closest evolutionary relatives, the non-human primates.
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New fellows
Six Washington University professors named AAAS fellows
Dec. 18,
2008 -- Six faculty members from Washington University in St. Louis have been named fellows of the American Association for the Advancement of Science (AAAS), the world's largest general scientific society. The highest honor awarded by AAAS, the rank of fellow is bestowed upon members by their peers in recognition of scientifically or socially distinguished efforts to advance science or its applications.
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Deciphering the genetic code
Model unravels rules that govern how genes are switched on and off
Dec. 4,
2008 --
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| Illustration by Michaela Hunt |
For years, scientists have struggled to decipher the genetic instruction book that details where and when the 20,000 genes in a human cell will be turned on or off. Different genes operate in each cell type at different times, and this careful orchestration is what ultimately distinguishes a brain cell from a liver or skin cell. Now, scientists at the School of Medicine report they have developed a model of gene expression in yeast that predicts with a high degree of accuracy whether a gene will be switched on or off.
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To each his own bacteria
Research in twins defines shared features of the human gut microbial communities: variations linked to obesity
Dec. 2,
2008 -- Trillions of microbes make their home in the gut, where they help to break down and extract energy and nutrients from the food we eat. Yet, scientists have understood little about how this distinctive mix of microbes varies from one individual to the next. Now, researchers at the School of Medicine have discovered that each individual carries a unique collection of bacteria, although the communities are more similar among family members.
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Partnership reaching students on a national level
Research-based undergraduate course expands beyond WUSTL
Nov. 25,
2008 --
Washington University in St. Louis is in the spotlight for its pivotal role in the Genomics Education Partnership, a collaborative effort to provide research experience in genomics to undergraduate classrooms across the country. At the helm of this mission is Sarah C.R. Elgin, Ph.D., WUSTL professor of biology and professor of education in Arts & Sciences, as well as professor of biochemistry & molecular biophysics and professor of genetics in the School of Medicine.
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