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Surgery: Transplant
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Precious gift
Grad student's kidney gives life to stranger
March 9,
2009 -- Last year, Chuck Rickert, a fifth-year student in the M.D./Ph.D. program at the School of Medicine, heard a show about kidney donation on National Public Radio's "Talk of the Nation." One of the callers, a man in his 50s on dialysis, said his blood type did not match any friends or family, and his only option for a new kidney was to wait for something bad to happen to a younger person. The distressed man's call stuck with Rickert, who eventually decided to anonymously donate one of his own kidneys.
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Research network
School of Medicine to lead international pediatric lung transplant research trials
March 14,
2008 -- The School of Medicine has received a five-year, $3.9 million grant to lead an international research effort designed to improve outcomes for children undergoing lung transplants. Lung-transplant patients are subject to more frequent infections, organ rejection and other complications than patients with other transplanted organs.
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Viewing cancer at the molecular level
Innovative molecular imaging center gets five-year, $10 million renewal grant
Nov. 8,
2007 -- An innovative cancer imaging center at the School of Medicine has received a five-year, $10 million grant from the National Cancer Institute (NCI). The grant will fund a second cycle of research at the Washington University Molecular Imaging Center, where scientists from many different specialties collaborate on advanced imaging projects.
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Inching closer to a cure
Cross-species transplant in rhesus macaques is step toward diabetes cure for humans
Oct. 18,
2007 --
In a new study with an eye on curing diabetes, senior investigator Marc Hammerman and a group of WUSM scientists successfully transplanted embryonic pig pancreatic cells destined to produce insulin into diabetic macaque monkeys - all without the need for risky immune suppression drugs that prevent rejection. The transplanted cells, known as primordia, are in the earliest stages of developing into pancreatic tissues. Within several weeks of the transplants, the cells became engrafted, or established, within the three rhesus macaque monkeys that received them. The cells also released pig insulin in response to rising blood glucose levels, as would be expected in healthy animals and humans.
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First-of-its-kind procedure
Bone marrow transplant performed for sickle cell disease
Sept. 25,
2007 -- Bone marrow transplants are best known for their potential to cure people with certain types of cancer. But they also hold promise for people with severe cases of sickle cell anemia, also known as sickle cell disease. Now, in a first-of-its-kind procedure, St. Louis Children's Hospital has performed a bone marrow transplant in a teenager with sickle cell disease, using cells from a donor who is unrelated to him.
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A model for success
First lung transplants in mice lay groundwork for preventing rejection in humans
July 11,
2007 -- Lung transplants have been performed successfully for more than 20 years in humans but never before in mice - until now. Surgeons at the School of Medicine have developed the first mouse model of lung transplantation, and they're hoping it will help explain why the success of the procedure in humans lags far behind other solid organ transplants.
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All smiles
University's 1,000th liver transplant recipient is all smiles one year later
Feb. 6,
2007 --
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| Photo by Robert Boston |
Kaidence Oliver, 22 months, entertained a number of members of the St. Louis media Jan. 17 during a celebration honoring her as the University's 1,000th liver transplant recipient. She received her new liver one year ago at St. Louis Children's Hospital.
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Treating the twitch
Dramatic results from combo therapy surprise Krabbé-disease researchers
Jan. 9,
2007 -- By all expectations, it shouldn't have worked as well as it did. A combination of bone marrow transplantation and gene therapy greatly lengthened the lives of laboratory mice doomed by a rapidly progressing, fatal neurodegenerative disorder also found in people. The School of Medicine researchers who made the discovery set out with low hopes for the combination therapy because on its own, each treatment was only modestly effective for the sick mice.
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Indebted donors
Researchers study reimbursing living organ donors for out-of-pocket expenses
Nov. 9,
2006 --
More than 80,000 people in the United States are on waiting lists for organ transplants. Some will have to wait for the death of a matching donor, but more and more people are receiving organs from living donors. In an effort to close the gap between organ supply and demand, researchers at Washington University School of Medicine, the University of Michigan and the American Society of Transplant Surgeons are studying ways to reimburse living donors for some of their out-of-pocket expenses when they choose to donate an organ.
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Fighting kidney rejection
Antibody reduces acute rejection in high-risk kidney transplant patients
Nov. 8,
2006 -- Nearly 70 percent of kidney transplant patients get short-term drug therapy initially administered during surgery to help prevent rejection. In the first head-to-head comparison of the two drugs most commonly given to ward off acute kidney rejection, an international study led by researchers at Washington University School of Medicine in St. Louis shows that one - anti-thymocyte globulin - is superior.
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