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Immune cell self-destruction

Gene regulates immune cells' ability to harm the body

July 16, 2009 -- A recently identified gene allows immune cells to start the self-destructive processes thought to underlie autoimmune diseases such as multiple sclerosis (MS) and rheumatoid arthritis, researchers at the School of Medicine have found.


Asthma testing

Washington University physicians provide free asthma screening at Science Center

May 11, 2009 -- If you've regularly been coughing, wheezing or short of breath, you may want to get tested for asthma at the Saint Louis Science Center on Saturday, May 16, 2009. As part of a nationwide program, Washington University School of Medicine physicians will be at the Science Center to test lung function and answer questions about asthma. The screenings are free.


Life lessons from an asthma coach

Asthma coaching can reduce hospitalizations in some children

May 4, 2009 -- Working with an asthma coach helps to significantly reduce hospitalizations of low-income, African-American children with asthma, results of a new, two-year study show. Researchers at the School of Medicine and the University of North Carolina at Chapel Hill worked with nearly 200 parents of children between 2-8 years old on Medicaid who had been hospitalized for asthma at St. Louis Children's Hospital.


Personalized asthma care

Children's characteristics may determine response to asthma drug

May 4, 2009 -- Certain characteristics of preschool-aged children at high risk for asthma could help physicians deliver more personalized and effective treatment. Researchers at the School of Medicine and five other sites nationwide found that children who showed the most improvement in days without wheezing using an inhaled corticosteroid drug were caucasian boys who had allergies and had a hospitalization or emergency department visit for asthma symptoms in the year prior to the trial.


Steroids for asthma

Asthma drugs need to be maintained for continued benefit

Feb. 17, 2009 -- Children whose asthma improved while taking steroid drugs for several years did not see those improvements continue after stopping the drugs, new results from a comprehensive childhood asthma study show. The results come from the Childhood Asthma Management Program (CAMP) clinical trial, in which more than 1,000 children age 5-12 were treated for mild to moderate asthma over more than four years.


The more the merrier

Study: Bird diversity lessens human exposure to West Nile Virus

Oct. 6, 2008 --
When the red, red robin comes bob, bob bobbin' along, think West Nile Virus (WNV).
This one's for the birds. A study by biologists at Washington University in St. Louis shows that the more diverse a bird population is in an area, the less chance humans have of exposure to West Nile Virus (WNV). Now, let's hear it for the birds. "The bottom line is that where there are more bird species in your backyard, you have much lower risk of contracting West Nile fever," said Brian Allan, doctoral candidate in biology in Arts & Sciences at Washington University in St. Louis.


Immune cell link intrigues Crohn's disease researchers

Form of Crohn's disease traced to disabled gut cells

Oct. 5, 2008 -- Scientists report in this week's Nature that they have linked the health of specialized gut immune cells to a gene associated with Crohn's disease, an often debilitating and increasingly prevalent inflammatory bowel disorder. The link to immune cells intrigued researchers at the School of Medicine because they and others believe Crohn's disease is caused by misdirected immune responses in the intestine that damage gut tissue.


Researchers zero in on potential contributor to MS

MS patients have higher spinal fluid levels of suspicious immune molecule

Sept. 29, 2008 -- A protein that helps keep immune cells quiet is more abundant in the spinal fluid of patients with multiple sclerosis (MS), further boosting suspicion that the protein, TREM-2, may be an important contributor to the disease.


Mold, mosquitoes follow flood

Flooded areas are now faced with a second wallop of mold, mosquitoes

July 21, 2008 -- The waters are receding, but the consequences of flooding in surrounding areas are only beginning to surface. These consequences are not just in physical and financial damage, but major indoor and outdoor health threats to children and their families, including disease-carrying mosquitoes and allergy-irritating mold.


Allergies and floods

Allergy expert has advice for flood victims

June 19, 2008 -- As if the emotional and financial impact of flood damage isn't bad enough, floodwaters can also bring health problems. H. James Wedner, professor of medicine and chief of the Division of Allergy and Immunology at the School of Medicine, says after the water recedes, damp homes and businesses are fertile grounds for mold growth, which can cause allergic reactions and asthmatic symptoms in sensitive people.



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Thursday, Dec. 2, 2004


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