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Endocrinology, Metabolism & Lipids

Physicians in the Division of Endocrinology, Diabetes and Metabolism diagnose and treat patients with endocrine and metabolic disorders such as thyroid diseases, diabetes, hyperlipidemia and osteoporosis. The division offers patients the very latest in diagnostic and treatment options.
Through research, our physicians also play a leading role in improving patient care. They conduct clinical studies to evaluate the latest treatments and diagnostic procedures, and perform basic science research to pave the way for new advances.
In addition, the division provides an excellent training ground for some of the nation's best medical students, resident physicians and postdoctoral fellows. The division operates one of the nation's top 10 training programs for this subspecialty.
| News Stories & Tip Sheets: |
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Moderation may be key for some diabetes drugs
 Moderate use averts failure of type 2 diabetes drugs in animal model

Oct. 27,
2008 -- Drugs widely used to treat type 2 diabetes may be more likely to keep working if they are used in moderation, researchers at the School of Medicine have found in a study using an animal model. The drugs, sulfonylureas, help type 2 diabetics make more insulin, improving control of blood sugar levels. But in most patients the effects of sulfonylureas are lost after several years of use, causing insulin secretion to shut down.

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New technique helps lower bad cholesterol
 Treatment filters bad cholesterol out of blood

Oct. 9,
2008 -- Diet and lifestyle changes, combined with medication, can lower the risk of heart attack and stroke in patients with high levels of so-called bad cholesterol. But some patients genetically predisposed to high levels of LDL (low-density lipoprotein) don't respond well to drug therapy. Now physicians at the School of Medicine can help these patients with a technique called LDL aphersis.

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Disease and DNA
 Gene variants linked to metabolic syndrome and HDL cholesterol levels

June 17,
2008 -- Nutrition researchers at the School of Medicine have identified five common genetic variations that increase the risk of metabolic syndrome, a group of factors linked to heart disease and diabetes. Another variant they found appeared to protect against the condition.

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Showing Stories 1 through 3 of 63.
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| Faculty Experts: |
Showing 3 Experts.
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Philip Cryer
 Irene E. and Michael M. Karl Professor of Endocrinology and Metabolism

The Karl Professor of Endocrinology and Metabolsim, Cryer is a world-renowned expert on diabetes complications and treatment, particularly the problems caused by low blood sugar (hypoglycemia), a common side effect of insulin therapy.

Expertise: Diabetes/hypoglycemia and other complications

Media assistance: /

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Jeffrey Moley
 Director, Translational and Clinical Investigation, Siteman Cancer Center

Moley is chief of endocrine and oncologic surgery at the School of Medicine and associate chief of surgery at the St. Louis Veteran's Administration Hospital. He is a world authority on endocrine surgery and endocrine cancers. Moley is especially known for his work on a hereditary cancer known as multiple ...

Expertise: Thyroid cancer, endocrine surgery, surgical oncology, musculoskeletal oncology, melanoma

Media assistance: (314) 286-0141 / ericsong@wustl.edu

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Clay F. Semenkovich
 Professor of Medicine and Professor of Cell Biology and Physiology

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| Semenkovich |
Semenkovich is known for his research on lipid metabolism, obesity and atherosclerosis.

Expertise: obesity, diabetes, lipid disorders, atheroscilerosis, lipid metaboism

Media assistance: (314) 286-0110 / jdryden@wustl.edu

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Showing 3 Experts.
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Hypoglycemia linked to dementia
Science News Web edition

April 14,
2009 -- A single episode of low blood sugar severe enough to require prompt medical attention increases a person's risk of developing dementia in old age, a study in people with diabetes suggests. "This is a worrisome association," says WUSTL endocrinologist Philip Cryer. But he cautions that an association doesn't prove that one factor causes the other.

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Steve Jobs' Illness Offers Complex Mystery
npr.org

Jan. 16,
2009 -- WUSTL endocrinologist Clay Semenkovich comments on Apple CEO Steve Jobs' cryptic statements regarding his health.

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Apple's Jobs Under Treatment to Gain Weight
The Wall Street Journal online

Jan. 7,
2009 -- WUSTL endocrinologist Clay Semenkovich is one of the specialists asked to comment on the diagnosis of Steve Jobs.

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Decoding The Health Statement Of Apple's Jobs
NPR.org

Jan. 7,
2009 -- When Apple CEO Steve Jobs put out a cryptic statement this week about his widely discussed weight loss, he practically guaranteed a new round of speculation about its cause. Includes comments by WUSTL endocrinologist Clay Semenkovich.

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Endocrinologists Weigh in on Steve Jobs' Hormonal Imbalance
U.S. News & World Report blogs

Jan. 7,
2009 -- Katy Marquardt blogs about what endocrinologists are saying about the diagnosis of Steve Jobs. Includes comments by WUSTL endocrinology chief Clay Semenkovich.

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