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The skinny on fat
Fat in the liver -- not the belly -- is a better marker for disease risk
Aug. 24,
2009 -- New findings from nutrition researchers at the School of Medicine suggest that it's not whether body fat is stored in the belly that affects metabolic risk factors for diabetes, high blood triglycerides and cardiovascular disease, but whether it collects in the liver. They report online in the journal PNAS Early Edition that when fat collects in the liver, people experience serious metabolic problems such as insulin resistance, which affects the body's ability to metabolize sugar.
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Liver fat key to diabetes, heart disease
Apple or pear shape is not main culprit to heart woes — it's liver fat
Dec. 3,
2008 -- Pear-shaped people who carry weight in the thighs and backside have been told for years they are at lower risk for high blood pressure and heart disease than apple-shaped people who carry fat in the abdomen. But in two studies, School of Medicine researchers report that body shape isn't the only marker of risk. Excess liver fat appears to be the key to insulin resistance, cholesterol abnormalities and other problems that contribute to diabetes and cardiovascular disease.
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Disease and DNA
Gene variants linked to metabolic syndrome and HDL cholesterol levels
June 17,
2008 -- Nutrition researchers at the School of Medicine have identified five common genetic variations that increase the risk of metabolic syndrome, a group of factors linked to heart disease and diabetes. Another variant they found appeared to protect against the condition.
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Elderly driver safety
Experts discuss aging's impact on ability to drive, find other transportation
April 28,
2008 -- Ensuring that the elderly have access to transportation while preventing age-related driving impairments will be the focus of the eighth annual Friedman Conference on Aging, "Are We Licensed for Life? Transportation and Driving Issues in an Aging Society."
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Happy birthday, Viagra!
Viagra celebrated for fixing more than one problem
April 1,
2008 -- Viagra, the breakthrough drug for battling male sexual dysfunction, hit the market 10 years ago. Now, physicians have now found an additional benefit for this type of drug. Many men are reluctant to visit the doctor but are eager to get the benefits of "the little blue pill." Their trips to the doctor to get a prescription may reveal underlying conditions including high blood pressure, undiagnosed or poorly controlled diabetes, heart disease or high cholesterol.
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Staying strong
Older women, not men, have a hard time maintaining muscle mass
March 25,
2008 -- Women over age 65 have a harder time preserving muscle than men of the same age, which probably affects their ability to stay strong and fit, according to research conducted at the School of Medicine and the University of Nottingham in the United Kingdom. For the first time, scientists have shown it is more difficult for older women to replace muscle that is lost naturally because of key differences in the way their bodies process food.
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Fewer calories. Longer life?
Researchers evaluate health benefits of calorie restriction
Feb. 21,
2008 -- A School of Medicine study is underway to determine whether reducing calories by 25 to 30 percent and eating nutrient-dense foods can improve health and lengthen lives.
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Caring for the elderly
Outreach program offers older adults free health assessments
Jan. 31,
2008 -- Medical professionals from Washington University and Barnes-Jewish College of Nursing are helping older adults in underserved areas of St. Louis identify and address wide-ranging health problems — from osteoporosis and frailty to impaired physical function and depression.
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Cardiac rejuvenation
Eat less or exercise more? Either way leads to more youthful hearts
Jan. 10,
2008 -- Overweight people who lose a moderate amount of weight get an immediate benefit in the form of better heart health, according to a study conducted at the School of Medicine. And the heart improvements happen whether that weight is shed by eating less or exercising more.
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New ways to fight obesity
Protein's role in lipid absorption may be important to future weight-loss strategies
July 5,
2007 -- Researchers at the School of Medicine have found that a protein absorbs lipids in the upper part of the intestine, and they believe its key role in this process may provide a novel approach for obesity treatment in the future. Principal investigator Nada Abumrad first identified the protein, CD36, that facilitates the uptake of fatty acids.
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