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Dermatology
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Red Alert
Skin's defense system may be link between childhood eczema and asthma
Aug. 27,
2009 --
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| Learning the language of cellular signaling: Mitsuru Morimoto, PhD, Shadmehr Demehri, PhD, and Raphael Kopan, PhD. |
Why do children with eczema so often get asthma? Experts in cellular signaling discovered how skin cells in danger might sound a body-wide alert. But lung cells in turn make an unfortunate response.
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Chronic wounds sow cancer seeds
Mice with skin condition help scientists understand tumor growth
July 6,
2009 -- Cancerous tumors sometimes form at the site of chronic wounds or injury, but the reason why is not entirely clear. Now researchers at theSchool of Medicine have engineered mice with a persistent wound-like skin condition, and the mice are helping them understand the tumor-promoting effects of long-standing wounds and injuries.
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Safe summer fun
Sun goers should protect themselves from harmful UV rays
June 15,
2009 -- Summertime is beach time, swimming pool time and gardening time. Most of us spend a lot more time in the sun during the summer months than during the rest of the year, and Washington University dermatologists say it's very important to protect ourselves from the sun's damaging rays.
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The atopic march
Researchers discover why eczema often leads to asthma
May 18,
2009 --
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| Top: normal lungs. Bottom: asthmatic lungs. |
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Many young children who get a severe skin rash develop asthma months or years later. Doctors call the progression from eczema, or atopic dermatitis, to breathing problems the atopic march. Now scientists at the School of Medicine have uncovered what might be the key to atopic march. They've shown that a substance secreted by damaged skin circulates through the body and triggers asthmatic symptoms in allergen-exposed laboratory mice.
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Researchers get to the root of serious skin condition
Scientists uncover new genetic variations linked to psoriasis
Jan. 26,
2009 -- Two international teams of researchers have made significant gains in understanding the genetic basis of psoriasis, a chronic skin condition that can be debilitating in some patients. Their research, involving thousands of patients, is reported in two studies published this week in the advance online Nature Genetics.
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Signal uncovered
Skin defects set off alarm with widespread and potentially harmful effects
May 27,
2008 -- When patches of red, flaky and itchy skin on newborn mice led rapidly to their deaths, researchers at the School of Medicine looked for the reason why. What they found was a molecular alarm system that serves as a sentinel to monitor the integrity of skin — the body's essential protective barrier. The fatal effects of raising this alarm in the lab mice suggests generally that certain kinds of impairments to the skin's structure can potentially trigger harmful effects in other areas of the body, according to the researchers.
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Beneath the surface
Researchers uncover new genetic links to psoriasis
April 3,
2008 -- In the first comprehensive study of the genetic basis of psoriasis, researchers at the School of Medicine have discovered seven new sites of common DNA variation that increase the risk of the troublesome skin condition.
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Treating bug bites
Dealing with bug bites
July 17,
2007 -- During the summer months many of us will be bitten by bugs. Dr. Julia Graves and Dr. Ann Martin at the School of Medicine have some advice about how to prevent and treat many types of bug bites. Most bug bites are harmless, but others need prompt medical treatment.
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A better way to tan
Safer alternatives to sunbathing may help prevent skin cancer
March 29,
2006 --
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| Today's tanning beds emit only UVA rays, but in much larger quantities than people normally receive from the sun. |
Spring has barely begun, but millions of Americans are already working on that summer tan. While tanning bed owners claim their rays are safer these days, scientific studies say otherwise. WUSM physician Lynn Cornelius provides safe alternatives to sunbathing in the following story from WFTV in Florida.
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Veggie block?
Sunscreen pill studied by researchers
Sept. 15,
2005 -- WUSM researchers believe a vitamin found in vegetables may serve as a safe, ingestible sunscreen for humans. They are currently looking for volunteers for a related study.
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