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Genetic data helps determine dosage
Genetic information can improve administration of anticoagulant
Feb. 18,
2009 -- Each year in the United States, doctors start about 2 million patients on warfarin (Coumadin™), an anticoagulant drug that's notoriously hard to administer. Now a study from the International Warfarin Pharmacogenetics Consortium (IWPC), which includes researchers from the School of Medicine, confirms that using a patient's genetic information can make it easier to get the warfarin dose right.
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Algorithm finds the network - for genes or the Internet
Math tool finds genetic communities that lead to disease
March 12,
2008 -- Human diseases and social networks seem to have little in common. However, at the crux of these two lies a network, communities within the network, and farther even, substructures of the communities. Weixiong Zhang, Ph.D., Washington University associate professor of computer science and engineering and of genetics, along with his Ph.D. student, Jianhua Ruan, has published an algorithm (a recipe of computer instructions) to automatically discover communities and their subtle structures in various networks.
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Personalized medicine
Genetic information makes it safer to prescribe common blood thinner
Aug. 30,
2007 -- Doctors prescribing blood thinners have had to go through a lengthy trial-and-error process to arrive at the optimal dose for their patients. But now the process can be faster and safer, thanks to research conducted at the School of Medicine. Researchers, along with colleagues at Saint Louis University and St. Louis College of Pharmacy, have developed an improved dosing formula for the widely prescribed anticoagulant warfarin (Coumadin®) that takes into account variations in two key genes
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Dean presents update to School of Medicine
Shapiro to give Dean's Update
Nov. 2,
2006 -- Dean Shapiro plans to give updates on the School of Medicine's key initiatives, including the tobacco-free initiative, addressing pandemic flu, and the New Interstate 64 project.
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Zapping playground problem
Engineers hope to provide smooth slide for kids with cochlear implants
May 4,
2006 --
For some deaf children, a plastic slide is a more formidable foe than the school wedgie-giver. Static electricity buildup from sliding down a plastic slide — instant summertime fun for those with normal hearing — can temporarily silence the world to cochlear implantees. Two electrical engineers at Washington University in St. Louis tested static electricity buildup — which can zap a cochlear implant — on sliding children to quantify the sparks. Thanks to some publicity and increased awareness, their research has inspired the St. Louis County Parks and Recreation Department to consider the problem, and an anti-static coating company to try to solve it. More...
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Unraveling the capsule
Thirty new genes should shed light on fungus M.O.
March 2,
2005 --
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| Michael R. Brent and Tamara L. Doering examine data from the C. neoformans microarray. |
A team of collaborators, including two researchers from Washington University in St. Louis, has sequenced the genomes of two strains of the fungus Cryptococcus neoformans (C. neoformans), one which is virulent, the other harmless. This work provides researchers with clues on how the fungus does its dirty work and a host of genes to study for a better understanding of fungal pathogens in general. Estimates are that about 15 percent of people with HIV will suffer at least one life-threatening infection of C. neoformans. In Africa, that could be as much as 40 percent of HIV sufferers.
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Eminent physician helps tsunami victims in Sri Lanka
Nuland tells of tsunami experience for Assembly Series
Feb. 24,
2005 --
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| Nuland |
Sherwin Nuland, physician, professor and best selling author, will relay his experiences working with tsunami victims in Sri Lanka for the Washington University Assembly Series at 11 a.m. Wednesday, March 23, in Graham Chapel. His talk is called "Tsunami Medical Diary."
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