Center for Computational Biology

Home Page: http://www.ccb.wustl.edu/ Location: 700 S. Euclid

Administratively, CMD was a division of the Institute for Biomedical Computing (IBC), under the joint responsibility of the Deans of the Schools of Engineering and Medicine. In 2000, after due deliberation, IBC was reorganized to include tenured faculty in three departments (Biochemistry and Molecular Biophysics, Biomedical Engineering, and Genetics) as the Center for Computational Biology, to focus on the unique opportunities presented by sequencing of the human genome as well as the genomes of other species, including pathogens. The presence at Washington University of the Genome Center, that has had such a prominent role in sequencing the human genome, has provided a rich environment for genomics and bioinformatics (Profs. Brent, Eddy, Gish, States and Stormo).

News Stories & Tip Sheets:

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The beat of a different drum Honoring time, computer greats consider evading time March 3, 2004 -- To meet design and cost changes, industry and government are considering clockless computing. Computing royalty, including Ivan Sutherland, the father of computer graphics, and Wesley A. Clark, the designer of the world's first personal computer, will gather at a computing symposium Friday, March 26th, 2004, from 1:00-5:30 p.m. at Washington University in St. Louis's Whitaker Hall Auditorium. As part of the University's 150th anniversary of its founding, participants will honor time by contemplating how computing can evade time as the industry prepares to go clockless.

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Equipped with new facilities and new faculty, the CCB continues to build on its international reputation in computational chemistry, drug design and bioinformatics by development of useful approaches in molecular design and application of computational biology to practical problems. New faculty with complementary expertise in computational biology are being recruited to CCB. In addition, internationally recognized computational chemistry software has resulted from the work of faculty and staff. These include the widely distributed TINKER package developed by the Jay Ponder group (distributed freely over the web,( http://dasher.wustl.edu/tinker/) the RACHEL™ package written by Dr. Chris Ho (Marshall group) and distributed by Tripos, Inc. and Prof. Nathan Baker's APBS program (Adaptive Poisson-Boltzmann Solver), which is also distributed freely over the web (http://agave.wustl.edu/apbs/).