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News Stories & Tip Sheets:

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Tracking biomarkers

Washington University in St. Louis and AstraZeneca announce Alzheimer's research collaboration

April 17, 2008 -- The School of Medicine and the pharmaceutical company AstraZeneca (NYSE:AZN) have announced a research collaboration that aims to develop new and improved ways to diagnose and treat Alzheimer's disease. The major focus of the alliance will be biomarkers, characteristic changes in the brain and spinal fluid that physicians can use to diagnose Alzheimer's disease and track its response to treatment.


Dance study

Tango provides fancy footwork for therapy

April 11, 2008 -- Despite a diagnosis of Parkinson's disease years ago, Wilfried Ute regularly dances the Argentine tango with his wife Adelt. Dancing has always been an integral part of their lives, and the couple jumped at the chance to participate in a Washington University study evaluating the therapeutic benefits of the tango for Parkinson's patients.


Producing plaques

Researchers close in on origins of main ingredient of Alzheimer's plaques

April 9, 2008 -- The ability of brain cells to take in substances from their surface is essential to the production of a key ingredient in Alzheimer's brain plaques, neuroscientists at the School of Medicine have learned. The researchers used a drug to shut down the intake process, known as endocytosis, in a mouse model of Alzheimer's disease. The change led to a 70 percent drop in levels of amyloid beta, the protein fragment that clumps together to form Alzheimer's plaques.



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Faculty Experts:

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Steven Petersen

James S. McDonnell Professor of Cognitive Neuroscience in Neurology

Petersen is chief of the Neuropsychology Division and a pioneer in using brain imaging to identify brain regions that contribute to attention, learning, memory and language. He also investigates the effects of disease and brain damage on these cognitive processes, bridging a range of psychological ...


Expertise: Neuroscience, cognitive neuroscience, neuropyschology, brain imaging, functional magnetic resonance imaging (fMRI), positron emission tomography (PET), attention, …

Media assistance: (314) 286-0122 / purdym@wustl.edu


David Clifford

Melba and Forest Seay Professor of Clinical Neuropharmacology in Neurology

Clifford, who is director of the AIDS Clinical Trials Unit (ACTU) at Barnes-Jewish Hospital, is a leading expert on the neurological complications of AIDS and their treatment and management. He has also participated in studies of epilepsy, Parkinson's disease and multiple sclerosis. Clifford is involved ...


Expertise: Neuropharmacology, HIV, AIDS, AIDS-related dementia, peripheral neuropathy, leukoencephalopathy, progressive multifocal leukoencephalopathy, …

Media assistance: (314) 286-0126 / pattoner@wustl.edu


David Gutmann, M.D., Ph.D.

Donald O. Schnuck Family Professor of Neurology

Gutmann is the founder and director of the Neurofibromatosis Clinical Program, which is dedicated to treating the common inherited tumor predisposition syndrome, neurofibromatosis (NF). Individuals with NF have an increased risk of developing brain tumors and other cancers. As national leader in the ...


Expertise: Brain tumors, cancer genetics, neurofibromatosis, molecular genetics, neurosciences, neurology

Media assistance: (314) 286-0122 / purdym@wustl.edu


David Carr

Associate Professor of Medicine and Neurology

Carr
Carr

Carr's interests are in caring for older adults in outpatient and long-term care settings. His current projects include research on the safety of older drivers, and evaluating the efficacy of units dedicated to oncology acute care and cardiology acute care for the elderly. Carr is the clinical director ...


Expertise: geriatrics, nutritional science, memory, aging

Media assistance: (314) 286-0109 / reckessg@wustl.edu


John Morris

Director and Principal Investigator, Alzheimer's Disease Research Center, Department of Neurology

John Morris
Morris
Download

John C. Morris, M.D., is the Harvey A. and Dorismae Hacker Friedman Distinguished Professor of Neurology, Professor of Pathology and Immunology and of Physical Therapy, and the Director of the Alzheimer Disease Research Center, Center for Aging, the Memory and Aging Project, and the Memory Diagnostic ...


Expertise: Alzheimer's disease, dementia, memory, aging, mild cognitive impairment

Media assistance: (314) 286-0122 / purdym@wustl.edu



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Related News Clips:

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Show More Clips
Study Details New Molecular Approach to Preventing Alzheimer's
The Washington Post and 7 others

April 25, 2008 -- German researchers are reporting a new approach to the possible prevention of the molecular "debris" that's associated with the development of Alzheimer's disease.
WUSTL neurology professor James Galvin called the German research "a novel idea."


Researchers zero in on Alzheimer's plaque origin
Agence France Presse and 13 others

April 10, 2008 -- WUSTL researchers have found that a key ingredient for the formation of Alzheimer's plaques is produced by a brain cell activity. WUSTL neurology professor and the study's first author John Cirrito comments.


Dementia Diagnosis May Relieve Patients
Associated Press and 110 others

March 13, 2008 -- Doctors often hesitate to tell patients they likely suffer from Alzheimer's disease or another form of dementia, fearing the news will overwhelm them.
Not only did the diagnosis not increase anxiety or depression among patients and their caregivers, but most were relieved to have symptoms explained and a way to find help.
But a WUSTL medical study suggests physicians need not worry. Researchers amd WUSTL psychology professor Brian Carpenter and neurology proessor John Morris comment.
The study, which appears in the March issue of the Journal of the American Geriatrics Society, gauged depression and anxiety two days before and two days after an evaluation and diagnosis.


Stress Can Help Trigger Stroke
The Washington Post and 8 others

March 4, 2008 -- The notion that stress can help bring on a stroke may have merit, British researchers say.
WUSTL neurology professor Mark Goldberg comments.


Experts Study Neuroscience Use in Courts
Associated Press and 82 others

March 3, 2008 -- Brain scans have emerged as potentially powerful tools in court battles over defendants' sanity. More defense attorneys are seeking scans showing brain damage or abnormalities that might have made it difficult for their clients to control violent impulses. Marcus E. Raichle, researcher of neurology and radiology at the School of Medicine, comments.



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westerhousej@wustl.edu

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Revised:

Thursday, Dec. 2, 2004


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