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Cardiology (Heart Services)

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Beta blocking
 Many African-Americans have a gene that prolongs life after heart failure

April 20,
2008 -- About 40 percent of African-Americans have a genetic variant that can protect them after heart failure and prolong their lives, according to research conducted at the School of Medicine and collaborating institutions. The genetic variant has an effect that resembles that of beta blockers, drugs widely prescribed for heart failure. The new study offers a reason why beta blockers don't appear to benefit some African-Americans.

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Avoiding vascular calcification
 Readily available treatment could help prevent heart disease in kidney patients

April 17,
2008 -- The estimated 19 million Americans living with chronic kidney disease (CKD) face a high risk of death from cardiovascular disease, usually related to high levels of blood phosphate. Now researchers at the School of Medicine have demonstrated that high blood phosphate directly stimulates calcification of blood vessels and that phosphate-binding drugs can decrease vascular calcification.

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Quiet killer
 WUSM clinic devoted to treating deadly, silent heart condition

April 9,
2008 -- Every so often we read a news report in which a young athlete collapses and dies during a competition — it's rare, but it happens. And when it does, often the cause is a silent heart condition called hypertrophic cardiomyopathy (HCM). The Hypertrophic Cardiomyopathy Clinic at the School of Medicine is devoted to diagnosis and treatment of HCM.

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Showing Stories 1 through 3 of 74.
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Showing 2 Experts.
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Genes Explain Race Disparity in Response to a Heart Drug
The New York Times
and 5 others

April 29,
2008 -- Doctors who treat patients with heart failure have long been puzzled that many black patients seem to not respond to a class of drugs called beta blockers.
Now researchers at WUSTL and U. Maryland have found that these nonresponsive patients have a slightly altered version of a gene that muscles use to control responses to nerve signals.
The discovery raises questions about whom to treat with beta blockers and how to decide, researchers say. But, they add, its implications go beyond heart failure.
WUSTL cardiologist and principal investigator Gerald Dorn comments.

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Angioplasty's golden era may be fading
USA Today
and 1 others

March 27,
2008 -- Three major studies published in the past two years indicate that using the angioplasty to open blocked arteries to treat chest pain, or angina, may be riskier and no more beneficial than medication. WUSTL cardiologist Michael Rich comments on the study.

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Weight loss by diet or exercise benefits heart
Reuters
and 7 others

Jan. 31,
2008 -- Shedding excess pounds may restore some of the heart's youth, whether the weight loss comes from eating less or exercising more, the results of a small study in the American Journal of Physiology suggests.
WUSTL's Sandor J. Kovacs, cardiology professor, is the senior researcher on the study and comments.

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Obese Kids Shows Signs Of Heart Trouble
WNBC.com (NY)
and 42 others

Oct. 19,
2007 -- Obese children show early signs of heart disease, according to WUSTL medical school researchers led by pediatric cardiologist Angela Sharkey.
The study was published in the Winter 2007 issue of the Journal of Cardiometabolic Syndrome.

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Heart surgery may eliminate migraines
United Press International

Jan. 12,
2007 -- Some people with migraines may be able to trace their problem to a hole in the heart that formed before birth, say WUSTL researchers led by cardiologist John Lasala.
WUSTL is participating in clinical trials.

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