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Cardiology (Heart Services)
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Expert diagnosis
Marfan clinic is largest in Midwest
Sept. 17,
2009 -- Marfan syndrome is almost as common as cystic fibrosis or muscular dystrophy, but doctors sometimes miss its signature traits that include unusual height, long, spindly arms, legs and fingers, a sunken chest and loose jointedness. To improve diagnosis, physicians at the School of Medicine and Barnes-Jewish Hospital have established the Marfan Clinic, which has quickly become the largest multidisciplinary in the Midwest for Marfans and related syndromes.
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Diabetics need D -- the vitamin
Research shows why low vitamin D raises heart disease risks in diabetics
Aug. 21,
2009 -- Low levels of vitamin D are known to nearly double the risk of cardiovascular disease in patients with diabetes, and now researchers at the School of Medicine think they know why. They have found that diabetics deficient in vitamin D can't process cholesterol normally, so it builds up in their blood vessels, increasing the risk of heart attack and stroke.
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Cancer succumbs to bee stings
Tumors feel the deadly sting of nanobees
Aug. 10,
2009 --
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| A computer simulation of a nanoparticle showing its core of perfluorocarbon (green) and its lipid coating (red, orange and blue). |
When bees sting, they pump poison into their victims. Now the toxin in bee venom has been harnessed to kill tumor cells by researchers at the School of Medicine. The researchers attached the major component of bee venom to nano-sized spheres that they call nanobees.
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Key leadership position
Dorn named Needleman Professor
July 9,
2009 --
Gerald W. Dorn II has been named the Philip and Sima K. Needleman Professor of Medicine at the School of Medicine. The professorship was established to support a faculty member holding a key leadership position within the BioMed 21 initiative, a multidisciplinary imperative to rapidly convert research findings into effective, individualized treatments.
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Heart valve 'redo'
Four out of 106 heart replacement valves from pig hearts failed
June 29,
2009 -- Pig heart valves used to replace defective aortic valves in human patients failed much earlier and more often than expected, says a report from cardiac surgeons at the School of Medicine. This is the first report to demonstrate this potential problem, the researchers say.
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A pacemaker for blood pressure?
Researchers evaluate iPod-sized device for hard-to-treat high blood pressure
May 27,
2009 --
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| Similar to a pacemaker, the iPod-sized device is implanted under the skin near the collarbone. |
Some 15 million Americans have high blood pressure that can't be controlled with medication, leaving them at high risk for early death, stroke, heart disease or kidney failure. Researchers at the School of Medicine are evaluating whether an investigational device can help these patients keep their blood pressure in check.
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CRUSADE to help heart attack patients
New tool calculates risk of bleeding in heart attack patients
April 14,
2009 -- With eight basic medical facts in hand, doctors can now estimate the risk of bleeding for a patient having a heart attack. Using clinical variables, researchers at the School of Medicine, Duke University and collaborating institutions have created a new method to estimate bleeding risk and help lessen the chances that heart attack patients will experience this common complication.
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Heart assist device
Artificial pump effectively backs up failing hearts
April 1,
2009 -- Patients with severe heart failure can be bridged to eventual transplant by a new, smaller and lighter implantable heart pump, according to a just-completed study of the device. Results of this third-generation heart assist device were reported at the 58th annual meeting of the American College of Cardiology on March 30.
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NIH five-year grant
Researchers receive $11 million to study causes of diabetic heart disease
Jan. 20,
2009 --
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| Gross (left) and Xianlin Han analyze samples |
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Researchers at the School of Medicine, led by heart specialist Richard Gross, are studying how altered fat metabolism causes heart failure in diabetic patients. They have received a five-year, $11 million grant from the National Institutes of Health to continue their investigations.
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Cardio chief named
Mann named director of cardiovascular division
Dec. 11,
2008 -- Douglas Mann has been named the Tobias and Hortense Lewin Professor and director of the Cardiovascular Division in the Department of Medicine at the School of Medicine. The appointment will be effective in March 2009. He will also become cardiologist-in-chief at Barnes-Jewish Hospital and director of the new Heart and Vascular Institute at Barnes-Jewish Hospital and Washington University.
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