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Biochemistry & Molecular Biophysics
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cWIDR
WUSTL center for study of women's infectious diseases officially opens
May 5,
2008 --
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| Photo courtesy of Scott Hultgren, John Heuser and Robyn Roth |
| A micrograph reveals an E. coli bacterium (in green) that is part of a community of bacteria known as a biofilm. |
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Washington University School of Medicine in St. Louis this week held opening ceremonies for a new center to study infectious diseases that preferentially affect women. The center for Women's Infectious Disease Research (cWIDR) will focus on issues such as microorganisms that cause urinary tract infections (UTIs), infections that lead to premature delivery, and potential contributing roles for microorganisms in life-threatening conditions such as cancer.
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Size matters
Researchers discover pathway to cell size, division
July 30,
2007 -- Researchers at Washington University in St. Louis have discovered through genetic analyses a metabolic pathway in bacteria comprised of just three genes, all known to be players in metabolism. This pathway was previously shown to be involved in synthesizing modified membrane lipids but data from Petra Levin's lab indicate that it also has a major role in cell division. This is the first identification of a pathway responsible for regulating bacterial cell size.
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Turning up the gas
Let the NO flow: discovery provides key to improving blood circulation, healing
April 6,
2007 --
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| An angiogram, or X-ray image of blood vessels |
Scientists have uncovered a new biomedical technique that could increase blood flow to alleviate problems associated with cardiovascular disease, diabetes and many surgical procedures. They found that blocking the action of a blood-clot-associated protein turns up the effect of a biologically produced gas that can open blood vessels and increase blood flow.
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| Faculty Experts: |
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Frank Yin
Stephen and Camilla Brauer Professor of Biomedical Engineering
Frank C. P. Yin, M.D., Ph.D., the Stephen and Camilla Brauer Professor of Biomedical Engineering and chair of the biomedical engineering department, is a world-renowned biomedical engineer. Yin heads a dynamic, young department, not yet five years old and already ranked among the top 20 in the nation. ...
Expertise: soft tissue mechanics, cell mechanics, hemodynamics
Direct contact: (314) 935-6164
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yin@biomed.wustl.edu
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Carl Frieden
The Wittcoff Professor of Biochemistry and Molecular Biophysics
Frieden studies protein folding, protein structure/function relationships, protein-protein interactions and the mechanism of enzymatic reactions. These investigations aim to understand the nature of the intermediate structures on the unfolding and refolding pathways, including the role of proteins ...
Expertise: Biochemistry, molecular biophysics, enzyme, protein folding, chaperones
Media assistance: (314) 286-0141 / ericsong@wustl.edu
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