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DNA cornucopia

Amaizeing: Corn genome decoded

Nov. 19, 2009 --
Iowa State
In recent years, scientists have decoded the DNA of humans and a menagerie of creatures but none with genes as complex as a stalk of corn, the latest genome to be unraveled. A team of scientists led by The Genome Center at the School of Medicine published the completed corn genome in the Nov. 20 journal Science, an accomplishment that will speed efforts to develop better crop varieties to meet the world's growing demands for food, livestock feed and fuel.


Microbial menagerie

Junk food binge alters community of microbes in the gut in less than a day

Nov. 11, 2009 -- Switching from a low-fat, plant-based diet to one high in fat and sugar alters the collection of microbes living in the gut in less than a day, with obesity-linked microbes suddenly thriving, according to new research at the School of Medicine. The study was based on transplants of human intestinal microbes into germ-free mice.


New syndrome found

Gene mutation may reveal clues for treating lung diseases

Oct. 15, 2009 -- A genetic mutation found in four children born with multiple abnormalities may provide insight into potential treatments for newborn lung distress and chronic obstructive pulmonary disease (COPD).


New leadership

Milbrandt named head of genetics

Oct. 7, 2009 --
Milbrandt
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Jeffrey D. Milbrandt has been named head of the Department of Genetics and the James S. McDonnell Professor at the School of Medicine. He brings a strength in basic and translational science to his new position and an appreciation of the expanding role of genetics in the diagnosis, prognosis and treatment of disease.


Improving care and treatment

Registry to track children with infantile spasms

Sept. 16, 2009 --
Paciorkowski
Researchers at the School of Medicine and the University of Chicago have launched what is believed to be the first worldwide, online registry of children with infantile spasms, a severe type of epilepsy that affects babies in the first few months of life.


Appointment announced

Sleckman named Conan Professor of Laboratory and Genomic Medicine

Aug. 11, 2009 --
Sleckman
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Barry P. Sleckman has been named the Conan Professor of Laboratory and Genomic Medicine at the School of Medicine. Washington University Chancellor Mark S. Wrighton and Larry Shapiro executive vice chancellor for medical affairs and dean of the School of Medicine, announced the appointment.


A shared link

Decoding leukemia patient genome leads scientists to mutations in other patients

Aug. 5, 2009 -- Decoding the complete DNA of cancer patients is giving scientists at the School of Medicine a clearer picture of the complexity of the disease and allowing them to see intriguing and unexpected genetic relationships among patients.


Fixing genetic breaks

New information about DNA repair mechanism could lead to better cancer drugs

July 16, 2009 --
Illustration of two proteins involved in DNA repair by artist Amy VanDonsel
Illustration of two proteins involved in DNA repair by artist Amy VanDonsel
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Researchers at the School of Medicine have shed new light on a process that fixes breaks in the genetic material of cells. The scientists studied protein molecules that have an important role in homologous recombination, which is one way that cells repair breaks in the DNA double helix. Their findings could lead to ways of enhancing chemotherapy drugs that destroy cancer cells by damaging their DNA.


Human Microbiome Project

$19 million to WU scientists to decode microbe DNA and explore links to disease

June 23, 2009 --
Human gut bacterium Enterococcus faecalis
Image courtesy of United States Department of Agriculture
Human gut bacterium Enterococcus faecalis
The National Institutes of Health (NIH) has awarded scientists at Washington University School of Medicine in St. Louis four grants totaling $19 million to explore the trillions of microbes that inhabit the human body and determine how they contribute to good health and disease. The grants are part of the Human Microbiome Project, an ongoing, ambitious effort to catalog the bacteria, viruses, fungi and other microorganisms that naturally coexist in or on the body.


What separates men from mice?

Of Mice and Men: Scientists unveil complete genome sequence of the mouse

May 29, 2009 -- Genetically speaking, what distinguishes a man from a mouse? U.S. and European scientists provide the answer in this week's PLoS Biology. They have described the finished genome sequence of the mouse, which, after the human, is only the second mammal to have its complete genome decoded.



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Thursday, Dec. 2, 2004


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