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 | Medical News Releases > University Groups > School of Medicine >
Cancer
Improved treatment
High-precision radiation therapy improves cervical cancer outcomes
Nov. 10,
2009 -- School of Medicine researhers have shown that highly targeted radiation therapy improves survival and lessens treatment-related complications in cervical cancer patients. The technique, called intensity-modulated radiation therapy, is widely accepted for treating many cancers of the pelvic region, head and neck, and central nervous system, but its for cervical cancer is not as common.
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Saving lives
New treatments improve outlook for pancreatic cancer patients
Oct. 21,
2009 -- A team of surgeons and oncologists at the Siteman Cancer Center at the School of Medicine and Barnes-Jewish Hospital is aggressively tackling pancreatic cancer — one of the deadliest forms of cancer — and conducting clinical trials of innovative treatment regimens.
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Spoken with feeling
StoryCorps captures stories from cancer survivors and their children
Sept. 28,
2009 --
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| Cancer survivor Kathy Ferrara and daughter Natalie continue their dialogue after participating in StoryCorps, a national oral history and research project. |
Cancer is a difficult diagnosis to acknowledge — especially what a parent with can-cer must explain. A StoryCorps project captures the emotional stories of survivors and may help others to say what must be said.
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Estrogen benefit
Low-dose estrogen shown safe and effective for metastatic breast cancer
Aug. 18,
2009 --
When estrogen-lowering drugs no longer control metastatic breast cancer, the opposite strategy might work. Raising estrogen levels benefited 30 percent of women whose metastatic breast cancer no longer responded to standard anti-estrogen treatment, according to research conducted at the School of Medicine and collaborating institutions.
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Cancer succumbs to bee stings
Tumors feel the deadly sting of nanobees
Aug. 10,
2009 --
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| A computer simulation of a nanoparticle showing its core of perfluorocarbon (green) and its lipid coating (red, orange and blue). |
When bees sting, they pump poison into their victims. Now the toxin in bee venom has been harnessed to kill tumor cells by researchers at the School of Medicine. The researchers attached the major component of bee venom to nano-sized spheres that they call nanobees.
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Cancer: weapons and suspects
WUSTL leads study of pediatric brain tumors
Aug. 10,
2009 -- The National Cancer Institute (NCI) has awarded a five-year, $4 million grant to researchers at the School of Medicine to use genetically-engineered mice to study the origins and potential treatments of pediatric brain tumors. David H. Gutmann, the Donald O. Schnuck Family Professor of Neurology, is principal investigator of the grant, which is part of the NCI's Mouse Models of Human Cancers Consortium. He is also on staff at Barnes-Jewish and St. Louis Children's hospitals.
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Fixing genetic breaks
New information about DNA repair mechanism could lead to better cancer drugs
July 16,
2009 --
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| Illustration of two proteins involved in DNA repair by artist Amy VanDonsel |
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Researchers at the School of Medicine have shed new light on a process that fixes breaks in the genetic material of cells. The scientists studied protein molecules that have an important role in homologous recombination, which is one way that cells repair breaks in the DNA double helix. Their findings could lead to ways of enhancing chemotherapy drugs that destroy cancer cells by damaging their DNA.
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'Consummate physician-scientist'
Michalski named vice chair of radiation oncology
July 8,
2009 --
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| Michalski |
Jeff M. Michalski, professor of radiation oncology, has been named vice chair and director of clinical programs of the Department of Radiation Oncology at the School of Medicine. He will oversee clinical operations at all treatment facilities, clinical and translational research, and all training and education.
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Safe summer fun
Sun goers should protect themselves from harmful UV rays
June 15,
2009 -- Summertime is beach time, swimming pool time and gardening time. Most of us spend a lot more time in the sun during the summer months than during the rest of the year, and Washington University dermatologists say it's very important to protect ourselves from the sun's damaging rays.
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Unraveling radiation resistance
Researchers find how a common genetic mutation makes cancer radiation resistant
June 8,
2009 -- Many cancerous tumors possess a genetic mutation that disables a tumor suppressor called PTEN. Now researchers at the School of Medicine have shown why inactivation of PTEN allows tumors to resist radiation therapy. The PTEN gene produces a protein found in almost all tissues in the body. This protein acts as a tumor suppressor by preventing cells from growing and dividing too rapidly.
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