Pathology

The Department of Pathology and Immunology at Washington University School of Medicine provides the Medical Center with these important services: surgical pathology, autopsy pathology and laboratory medicine. It is also responsible for the teaching of medical and graduate students and the training of postgraduates in an extensive research program. The department consists of the Divisions of Anatomic Pathology, Laboratory Medicine, Neuropathology and Molecular Pathology/Immunology.

News Stories & Tip Sheets:

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Problem cells

Suspected cause of type 1 diabetes caught "red-handed" for the first time

May 8, 2008 -- Scientists at the School of Medicine working with diabetic mice have examined in unprecedented detail the immune cells long thought to be responsible for type 1 diabetes. Researchers were able to examine the immune cells from isolated insulin-making structures in the pancreas known as the islets of Langerhans.

Algorithm finds the network - for genes or the Internet

Math tool finds genetic communities that lead to disease

March 12, 2008 -- Human diseases and social networks seem to have little in common. However, at the crux of these two lies a network, communities within the network, and farther even, substructures of the communities. Weixiong Zhang, Ph.D., Washington University associate professor of computer science and engineering and of genetics, along with his Ph.D. student, Jianhua Ruan, has published an algorithm (a recipe of computer instructions) to automatically discover communities and their subtle structures in various networks.

Broad-spectrum antibiotics battle IBD

Scientists successfully treat new mouse model of inflammatory bowel disease

March 5, 2008 -- Researchers trying to improve cancer immune therapy have made an unexpected find: They've produced the most accurate mouse model to date of inflammatory bowel disease (IBD), a cluster of conditions that afflict approximately 1.4 million Americans with abdominal pain, constipation and diarrhea.

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Faculty Experts:

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Stanford Peng

Assistant professor of internal medicine

Peng is working to uncover the molecular and genetic underpinnings of autoimmune conditions such as lupus, inflammatory bowel disease and some forms of arthritis. His lab was the first to find firm experimental evidence supporting a radical new theory for what immune cells are like when they're not ...

Expertise: lupus, arthritis, inflammatory bowel disease, T cell, B cell, immunology, autoimmunity

Media assistance: (314) 286-0122 / purdym@wustl.edu

John Morris

Director and Principal Investigator, Alzheimer's Disease Research Center, Department of Neurology

Morris

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John C. Morris, M.D., is the Harvey A. and Dorismae Hacker Friedman Distinguished Professor of Neurology, Professor of Pathology and Immunology and of Physical Therapy, and the Director of the Alzheimer Disease Research Center, Center for Aging, the Memory and Aging Project, and the Memory Diagnostic ...

Expertise: Alzheimer's disease, dementia, memory, aging, mild cognitive impairment

Media assistance: (314) 286-0122 / purdym@wustl.edu

Roy Curtiss

Professor emeritus of biology in Arts & Sciences

Roy Curtiss

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Has developed a Salmonella-based oral vaccine for livestock that can free animals from the virulent strain of Salmonella that causes food-poisoning in humans. His vaccine has received FDA approval for swine and poultry and is on the market. Curtiss also has obtained patents for the use of transgenic ...

Expertise: Salmonella, food poisoning, FDA, vaccine, genetic engineering, microbial, pathogen, …

Direct contact: (314) 935-6819 / rcurtiss@wustl.edu

Michael Diamond

Assistant professor of molecular microbiology

Diamond is an expert in the effects of West Nile Virus (WNV) and other mosquito-borne viruses on the human immune and nervous systems. He uses mouse models to study the viruses' ability to infect the central nervous system and has identified genetic factors that can increase the chances a WNV infection ...

Expertise: Dengue, West Nile Virus, West Nile encephalitis, vaccine, vaccination, immunity, hemorrhagic fever, …

Media assistance: (314) 286-0122 / purdym@wustl.edu

Jonathan Gitlin

Helene B. Roberson Professor of Pediatrics

Gitlin

Jonathan Gitlin, M.D., the Helene B. Roberson Professor of Pediatrics and professor of pathology and immunology, specializes in arthritis, rheumatology and diseases and disorders of the immune system in children.

Expertise: Arthritis, immune system, children, rheumatology, pathology, immunology

Media assistance: (314) 286-0119 / leydigk@wustl.edu

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