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Cell Biology & Physiology


URL: http://mednews.wustl.edu/group/page/normal/68.html

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Jim Dryden
Assoc. Dir. of Broadcast Services
jdryden@wustl.edu

(314) 286-0110

News Stories & Tip Sheets:

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The way cells die matters to our bodies

How cells die determines whether immune system mounts response (http://mednews.wustl.edu/news/page/normal/12011.html)

July 17, 2008 -- Every moment we live, cells in our bodies are dying. One type of cell death activates an immune response while another type doesn't. Now researchers at the School of Medicine and St. Jude's Children's Research Hospital in Memphis have figured out how some dying cells signal the immune system. They say the finding eventually could have important implications in the treatment of autoimmune diseases and cancer.


An alternative to chemotherapy

Nanoparticles tackle pediatric brain tumors (http://mednews.wustl.edu/tips/page/normal/11996.html)

July 14, 2008 --
Wooley
Wooley
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An interdisciplinary team of researchers at Washington University in St. Louis, led by Karen L. Wooley, Ph.D., James S. McDonnell Distinguished University Professor in Arts & Sciences, is a step closer to delivering cancer-killing drugs to pediatric brain tumors, similar to the tumor that Senator Ted Kennedy is suffering from. Such tumors are often difficult to completely remove surgically; frequently, cancerous cells remain following surgery and the tumor returns. Chemotherapy, while effective at treating tumors, often harms healthy cells as well, leading to severe side effects especially in young children that are still developing their brain functions. In an effort to solve this problem, the Wooley lab has developed polymeric nanoparticles that can entrap doxorubicin, a drug commonly used in chemotherapy, and slowly release the drug over an extended time period.


Revving up the immune system

Control switches found for immune cells that fight cancer, viral infection (http://mednews.wustl.edu/news/page/normal/11984.html)

July 7, 2008 -- Medical science may be a significant step closer to climbing into the driver's seat of an important class of immune cells, researchers at the School of Medicine report in Nature Immunology.



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Faculty Experts:

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Ralph Quatrano

Ralph S. Quatrano, Ph.D., is the Spencer T. Olin Professor in Arts and Sciences and chair of the Department of Biology at Washington University in St. Louis. He is internationally known for his plant science work on patterns of embryo formation, and how the patterns lead cells to acquire traits or ...


Expertise: Plants, plant biology, botany, moss, genome, algae, genes, …

Direct contact: (314) 935-6850 / rsq@wustl.edu
Shirley Sahrmann

Professor of cell biology and physiology (http://mednews.wustl.edu/sb/page/normal/721.html)

Clinically, Sahrmann specializes in musculoskeletal pain syndromes and neuromuscular dysfunction syndromes. Her research interests include motor control and the classification of musculoskeletal pain syndromes.


Expertise: musculoskeletal pain syndromes, neuromuscular dysfunction syndromes, motor control

Media assistance: (314) 286-0111 / williamsdia@wustl.edu


Keith Hruska

Professor of nephrology (http://mednews.wustl.edu/sb/page/normal/714.html)

Hruska is a leader in studies of the links between the kidney and the skeleton, which can cause devastating side effects for patients with chronic kidney disease (CKD). Kidneys and bones produce factors that support each other's development and maintenance, and when CKD damages the kidney and reduces ...


Expertise: kidney, chronic kidney disease, bone, bone weakening, adynamic bone disorder, secondary hyparathyroidism, bone morphogenetic protein

Media assistance: (314) 286-0122 / purdym@wustl.edu


Joseph Ackerman

William Greenleaf Eliot Professor of Physical Chemistry in Arts & Sciences (http://mednews.wustl.edu/sb/page/normal/496.html)

Joseph Ackerman
Joseph Ackerman
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Joseph J. H. Ackerman, Ph.D. is William Greenleaf Eliot Professor of Chemistry and chair of the chemistry department. His work is concerned primarily with the development and application of magnetic resonance spectroscopic and imaging techniques for the study of functional biophysical and physiologic ...


Expertise: magnetic resonance techniques, spectroscopic techniques, imaging techniques, functional biophysical, physiologic events, intact biological systems, isolated cell preparations, …

Direct contact: (314) 935-6593 / ackerman @wuchem.wustl.edu


Frank Yin

Stephen and Camilla Brauer Professor of Biomedical Engineering (http://mednews.wustl.edu/sb/page/normal/349.html)

Yin
Yin
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Frank C. P. Yin, M.D., Ph.D., the Stephen and Camilla Brauer Professor of Biomedical Engineering and chair of the biomedical engineering department, is a world-renowned biomedical engineer. Yin heads a dynamic, young department, not yet five years old and already ranked among the top 20 in the nation. ...


Expertise: soft tissue mechanics, cell mechanics, hemodynamics

Direct contact: (314) 935-6164 / yin@biomed.wustl.edu



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Related News Clips:

Showing 3 Clips.
Insights Into Cell Movement Likely to Aid Immune Study, Cancer Research
ScienceDaily.com and 5 others

Jan. 9, 2008 -- WUSTL School of Medicine scientists have used yeast cells to better understand a collection of proteins associated with the formation of actin networks, which are essential to cell movement. WUSTL cell biology and physiology Professor and senior study author John Cooper, WUSTL physics professor Anders Carlsson, and Brian Galletta, a postdoctoral scholar in Cooper's lab, comment.


Study suggests new factor contributing to heart disease
St. Louis Post-Dispatch and 35 others

May 26, 2005 -- According to a new WUSTL study published in Nature, faulty metabolism can damage your heart. This new study indicates that bad metabolism could cause blockages in blood vessels, which can lead to heart attacks and strokes. WUSTL cell biologist and physiologist Clay Semenkovich comments.


Need to eat some fat to burn fat
myDNA.com and 9 others

May 10, 2005 -- Working with mice, WUSTL researchers led by cell biology and physiology professor Clay Semenkovich found that where fat comes from determines whether the body can metabolize it effectively. Fat around the belly, thighs or bottom can't be burned efficiently unless "new" fat is eaten in the diet or made in the liver.




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