Media Assistance:
 Jim Dryden Assoc. Dir. of Broadcast Services jdryden@wustl.edu (314) 286-0110 |
Research interests in the Washington University Department of Genetics include the basic molecular and developmental genetics of model eukaryotic systems, as well as the mapping and identification of genes responsible for important human hereditary diseases.
Genome research is a major focus of the Department. One of the largest genome centers in the world, the Washington University Genome Sequencing Center, is part of the Department.
The department is strongly interdisciplinary, with expertise that ranges from molecular biology and classical genetics, to the engineering of new tools and machines for genome analysis, to the development of computer algorithms and software for analyzing DNA and protein sequences.
Most graduate students in the Department are admitted through the Division of Biology and Biomedical Sciences. Some students may also be admitted through the Biomedical Engineering Program in the School of Engineering.
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| New generation of heart disease treatment Gene directs stem cells to build the heart (http://mednews.wustl.edu/news/page/normal/11973.html) July 2, 2008 --
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| Disease and DNA Gene variants linked to metabolic syndrome and HDL cholesterol levels (http://mednews.wustl.edu/news/page/normal/11931.html) June 17, 2008 -- Nutrition researchers at the School of Medicine have identified five common genetic variations that increase the risk of metabolic syndrome, a group of factors linked to heart disease and diabetes. Another variant they found appeared to protect against the condition. |
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| Genetic marker Gene variation linked to earlier onset of Alzheimer's symptoms (http://mednews.wustl.edu/news/page/normal/11867.html) June 9, 2008 --
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| Faculty Experts: |
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| David Gutmann, M.D., Ph.D. Donald O. Schnuck Family Professor of Neurology (http://mednews.wustl.edu/sb/page/normal/586.html) Gutmann is the founder and director of the Neurofibromatosis Clinical Program, which is dedicated to treating the common inherited tumor predisposition syndrome, neurofibromatosis (NF). Individuals with NF have an increased risk of developing brain tumors and other cancers. As national leader in the ... Expertise: Brain tumors, cancer genetics, neurofibromatosis, molecular genetics, neurosciences, neurology Media assistance: (314) 286-0122 / purdym@wustl.edu |
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| Alan Templeton Professor of Biology in Arts & Sciences (http://mednews.wustl.edu/sb/page/normal/341.html)
Templeton applies molecular genetic techniques and statistical population genetics to a variety of problems in evolutionary and conservation biology. He explores natural selection in various species, genetic variability, the role of lipid metabolic genes in coronary artery disease in humans, and the ... Expertise: evolution of HIV, evolutionary and conservation biology, genetic variability, lipid metabolic genes, molecular genetics, natural selection Direct contact: (314) 935-6868 / temple_a@biology.wustl.edu |
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| Alison M. Goate Professor of Genetics and Psychiatry (http://mednews.wustl.edu/sb/page/normal/207.html)
A professor of genetics in psychiatry, Alison Goate is a molecular geneticist who discovered the first genetic mutation that causes a form of Alzheimer's disease. Expertise: Alzheimer's disease, amyloid, genetics, psychiatry, genetic mutation, amyloid-beta, disease-causing mutations Media assistance: (314) 286-0110 / jdryden@wustl.edu |
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| Paul Goodfellow Professor of Surgery (http://mednews.wustl.edu/sb/page/normal/224.html) The Goodfellow laboratory is investigating the genetic alterations that underlie development of uterine endometrial cancers. Endometrial cancer is the most common gynecologic malignancy in the United States. Like many cancers, uterine endometrial cancers are hormonally- responsive tumors. The genetic ... Expertise: Cancer genetics, cancer, DNA, genetics, gene expression Media assistance: (314) 286-0141 / ericsong@wustl.edu |
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| Howard McLeod director of the pharmacology core at the Siteman Cancer Center (http://mednews.wustl.edu/sb/page/normal/223.html) There is a high degree of variation in patient response to medicines. The McLeod laboratory uses genetic tools to perform in vitro, ex vivo, and clinical evaluations to discover, validate, and apply molecular predictors of therapeutic outcome. This includes candidate gene and genome-wide human association ... Expertise: pharmacogenetics, pharmacology, translational research, tumor markers, chemotherapy Media assistance: (314) 286-0141 / ericsong@wustl.edu |
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| A Gene Map for the Cute Side of the Family
The New York Times May 13, 2008 -- When scientists announced last week that they had deciphered the complete genetic playbook for the duck-billed platypus, the public reacted with unexpected enthusiasm. WUSTL genetics professor and co-author Wesley Warren explains the attraction for researchers. |
| Looking at Genome of the Platypus
The New York Times and 3 others May 8, 2008 -- An international scientific team, which announced the first decoding of the platypus genome, said the findings provided "many clues to the function and evolution of all mammalian genomes," including that of humans, and should "inspire rapid advances in other investigations of mammalian biology and evolution." The research was conducted by a group of almost 100 scientists led by WUSTL genetics professor Wesley Warren. |
| Platypus Genome Reveals Secrets of Mammal Evolution
National Geographic News May 8, 2008 -- Decoding the platypus genome has long been an important goal for biologists seeking to understand the origins of mammal evolution. That goal was reached by the team of project leader, WUSTL's Wesley Warren. |
| Platypus Is Even More Strange Than It Looks
NPR All Things Considered and 1 others May 8, 2008 -- NPR's Joe Palca reports that scientists have now completed a draft DNA sequence of the platypus genome that reveals reptilian and mammalian elements. WUSTL genetics professor Richard Wilson, who directed the platypus genome project at WUSTL, comments. |
| Which Genetic Tests are Really Worth Getting?
The Wall Street Journal May 1, 2008 -- With Congress poised to eliminate a big barrier to genetic testing for risk of certain diseases, consumers still face challenges in figuring out which ones offer useful information. Despite heavy marketing by some genetic-test makers, the wide use of genetic tests has been held back by a variety of factors, including questions about the tests' usefulness and concerns that results could be used by employers and insurers to discriminate against people. Critics argue that many tests can't accurately identify which people are at risk for various illnesses. WUSTL medical researcher Brian Gage comments. Includes Web links to learn more about genetic testing. |
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