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 | Medical News Releases > Faculty Experts at Washington University in St. Louis >

Professor of Medicine
Expertise: gerontology research, calorie restriction
Bio:
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| Holloszy |
Holloszy is a pioneer in understanding the impact of exercise training on the quality of life of the elderly. One of the leading figures in gerontology research, his seminal studies include investigations into whether exercise reverses some of the deterioration in functional capacity that has traditionally been considered an inevitable part of aging, and a recent study showing severe calorie restriction reduces the risk of heart attack, stroke and diabetes.

| News Stories & Tip Sheets: |
Showing 4 Stories.
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Fewer calories. Longer life?
 Researchers evaluate health benefits of calorie restriction

Feb. 21,
2008 -- A School of Medicine study is underway to determine whether reducing calories by 25 to 30 percent and eating nutrient-dense foods can improve health and lengthen lives.

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CALERIE study
 Calorie restriction appears better than exercise at slowing primary aging

May 31,
2006 -- Investigators at the School of Medicine have found that eating a low-calorie yet nutritionally balanced diet lowers concentrations of a thyroid hormone called triiodothyronine (T3), which controls the body's energy balance and cellular metabolism.

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Thinner and younger
 Preliminary study demonstrates calorie restriction reduces markers of aging

April 4,
2006 --
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| Restricting calories may mean living longer. |
Can eating a low-calorie yet nutritionally balanced diet extend human life as it does in rodents? Preliminary research suggests it might, so researchers at Washington University School of Medicine in St. Louis are launching a long-term study to find out. More...

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DHEA may help fight off fat, diabetes
 Abdominal fat decreases, insulin action improves when elderly take hormone

Nov. 10,
2004 --
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| Abdominal fat reduction with DHEA use |
In a six-month study of elderly people, researchers at the School of Medicine found that the hormone dehydroepiandrosterone (DHEA) significantly reduced abdominal fat and improved insulin action. This finding suggests that DHEA may be able to counter the increase in abdominal fat and accompanying increased risk for diabetes that very often occurs as we grow older.

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Showing 4 Stories.
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Cut calories for a younger heart
CBS News, St. Louis Post-Dispatch
and 115 others

Jan. 13,
2006 -- A very low calorie — that cut calories by as much as 40% of your normal intake — can help the heart age more slowly, according to researchers who released what they call the first-ever human study on the subject. Results showed that people on the strict diet had younger hearts than normal-weight people on a typical Western diet. WUSTL medical professor and lead author Luigi Fontana and colleague John Holloszy comment.

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