Washington University in Saint Louis

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Samuel Klein

URL: http://mednews.wustl.edu/sb/page/normal/197.html

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Jim Dryden
Assoc. Dir. of Broadcast Services
jdryden@wustl.edu
(314) 286-0110

Danforth Professor

Expertise: Obesity, nutrition, weight loss

Bio:
Klein
The Danforth Professor of Medicine and Nutritional Sciences, Samuel Klein is an internationally renowned expert on obesity and weight loss.

Education:


News Stories & Tip Sheets:

Showing Stories 1 through 5 of 16.  - Show More
Toxic tummy

Belly fat may drive inflammatory processes associated with disease (http://mednews.wustl.edu/tips/page/normal/8947.html)

March 8, 2007 --
An abdominal MRI scan showing the locations of subcutaneous and visceral fat
An abdominal MRI scan showing the locations of subcutaneous and visceral fat
As scientists learn more about the key role of inflammation in diabetes, heart disease and other disorders, new research from Washington University School of Medicine in St. Louis suggests that fat in the belly may be an important promoter of that inflammation. It's well known that excess fat is associated with disease, but the researchers have confirmed that fat cells inside the abdomen are secreting molecules that increase inflammation. It's the first evidence of a potential mechanistic link between abdominal fat and systemic inflammation. More... (http://mednews.wustl.edu/tips/page/normal/8947.html)


Under the skin

Hidden abdominal fat may pose greater health risks than visible body fat (http://msnbc.msn.com/id/12919730/site/newsweek/)

May 24, 2006 -- A growing number of Americans are overweight or obese, but where they store those extra pounds may be as important as how many extra pounds they carry. Visceral fat, hidden inside the abdomen, has been linked to higher rates of various metabolic ailments, including diabetes and heart disease.


Controlling the fat

Researchers study effects of weight loss in adolescents (http://mednews.wustl.edu/news/page/normal/6929.html)

April 3, 2006 -- A team of researchers at the School of Medicine is studying how fatty liver disease affects sugar and fat metabolism in overweight adolescents and how losing weight affects the condition. In the last 30 years, the number of overweight children has doubled in the United States, and overweight children are at increased risk for the problem.


Fighting fat

Weighing answers to obesity (http://magazine.wustl.edu/Winter05/SamuelKlein.htm)

Jan. 26, 2006 --
Klein
Klein
Humans are genetically programmed to eat food and store energy as fat. Americans today have a variety of energy-saving devices at their disposal, which actually makes it hard for them to burn off that stored energy, says Samuel Klein, director of the Center for Human Nutrition. Klein and his colleagues are dedicated to improving health and preventing obesity using pioneering research, community programs and nutrition education.


'Tis the season

Preventing holiday weight gain is easier than losing extra pounds (http://msnbc.msn.com/id/10039210/site/newsweek/)

Nov. 17, 2005 --
Holiday food can add unwanted pounds.
Holiday food can add unwanted pounds.
January is no stranger to extra pounds. As long as Americans have celebrated their fall and winter holidays, many have entered the new year carrying a little extra baggage. With weight becoming an ever-growing concern in the U.S., WUSM nutrition expert Samuel Klein discusses ways to avoid extra holiday pounds in the following Newsweek column.



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Clips:

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Study: When kids become teens, they get sluggish
Associated Press Online and 79 others

July 16, 2008 -- One of the largest studies of its kind shows just how sluggish American children become once they hit the teen years: While 90 percent of 9-year-olds get a couple of hours of exercise most days, fewer than 3 percent of 15-year-olds do.
WUSTL nutrition expert Samuel Klein, director of WUSTL medical school's Human Nutritioin Center, said the research provides a more powerful snapshot than previous studies.


Longevity quest moves slowly from lab to life
MSNBC.com and 2 others

April 23, 2008 -- Human studies plus laboratory work with yeast, worms, flies and rodents are propelling scientists closer to understanding what causes aging, how to delay it -- and how to translate such progress from the lab to real life.
One of the studies mentioned was the first calorie restriction clinical trials conducted by WUSTL and LSU.


Gut Check: Why Doctors Say Not All Fat Is Created Equal
The Wall Street Journal and 2 others

April 15, 2008 -- The recent report that having a pot belly in your 40s roughly triples your risk of dementia in later life is just the tip of an ominous iceberg. WUSTL research on liposuction in which found no change in the women's cholesterol levels, triglycerides, insulin sensitivity or other health risks. "If they had lost that much fat by dieting, they would have substantially improved their metabolic profile, but they didn't," says Samuel Klein, director of WUSM's Center for Human Nutrition and the study's principal investigator.



Additional Background: Klein, the Danforth Professor of Medicine and Nutritional Sciences, also is director of the Division of Geriatrics and Nutritional Sciences at the School of Medicine. He directs the University's Center for Human Nutrition, and is associate program director of the University's General Clinical Research Center and medical director of both the Washington University Weight Management Center and the Barnes-Jewish Hospital Nutrition Support Service. Klein has developed several new clinical and research programs aimed at prevention and therapy for nutrition-related diseases. Klein has developed several new clinical and research programs aimed at prevention and therapy for nutrition-related diseases. In his role with the Washington University Weight Management Center, Klein helps provide patients with long-term therapy for obesity. Current clinical research includes assessment of diet comosition on weight loss and the regulation of fat metabolism in obesity.
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•JoAnne Wilson
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